Drugs
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Drugs are wondrous objects that allow you to trade your long-term well-being for immediate survival.
Unlike regular consumables, many drugs have a chance of making you Addicted.
Chem Reliant characters automatically become addicted to whatever drugs they use, always suffering stat penalties between doses.
Drug effects wear off after a while, as indicated by an on-screen countdown timer which can be reset at any time by taking another dose.
Healing drugs
| Picture | Name | Effects | Attack delay |
Crafting requirements |
Required materials |
|---|---|---|---|---|---|
| Weak Healing Powder | +30 HP | 800 ms | Crafting 25% Level 5 |
1 x Broc Flower 1 x Xander Root | |
| Stimpak | +50 HP | 1000 ms | Crafting 50% Level 24 Workbench |
2 x Broc Flower 2 x Xander Root 1 x Chemical component | |
| Super Stimpak | +80 HP | 1300 ms | Crafting 75% Level 50 Adv. Workbench |
1 x Meat Jerky 1 x Chemical component 1 x Blueprint | |
| Mega Stimpak | +110 HP | 1300 ms | Crafting 150% Level 250 Adv. Workbench |
40 x High Quality Chemical Component 20 x Electronic Parts 30 x Refined Uranium Ore 100 x Xander Root 1 x Blueprint | |
| Hypo (T5) | +50% HP | 1000 ms | N/A | N/A |
Utility drugs
| Picture | Name | Effects | Addiction | Crafting requirements |
Required materials |
|---|---|---|---|---|---|
| Antidote | -25 to Poison Level Removes Slow instantly |
N/A | Crafting 25% Level 5 |
1 x Scorpion Tail 1 x Plastic Bottle | |
| Drug Antidote | Removes drug effects and addictions | N/A | Crafting 150% Level 250 Adv. Workbench |
50 x High Quality Chemical Component 40 x Meat Jerky 10 x Glass Bottle 1 x Blueprint | |
| Rad-X | +50% Rad Resistance +10% Rad Resistance Cap -5% max hit chance -5% critical chance |
N/A | Crafting 75% Level 50 Adv. Workbench |
2 x Chemical Component 1 x Blueprint | |
| RadAway | Reduces your current irradiation level by 50% (Cooldown: 15 minutes, can be cleared like any other drug timer) |
10% chance | Crafting 50% Level 24 Workbench |
2 x Chemical Component 3 x Minerals 1 x Blueprint |
Regular drugs
| Picture | Name | S | P | E | C | I | A | L | Effects | Addiction | Crafting requirements |
Required materials |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jet | -1 AP | Crafting 75% Level 50 Adv. Workbench |
20 x Brahmin Shit 10 x Chemical Component 1 x Blueprint | |||||||||
| Mentats | +2 | +2 |
|
-1 Charisma | Crafting 75% Level 50 Adv. Workbench |
30 x High Quality Chemical Component 1 x Blueprint | ||||||
| Buffout | +2 | +2 | -1 EN | Crafting 75% Level 50 Adv. Workbench |
10 x Meat 10 x Meat Jerky 1 x Blueprint | |||||||
| Healing Powder | -3 |
|
-10 healing rate | Crafting 75% Level 50 Adv. Workbench |
5 x Broc Flower 5 x Xander Root 1 x Blueprint | |||||||
| Psycho | -3 |
|
-3% to all DRs | Crafting 75% Level 50 Adv. Workbench |
10 x Meat 30 x Chemical Component 1 x Blueprint | |||||||
| Mutie |
|
-3 to all DTs | Crafting 75% Level 50 Adv. Workbench |
10 x Meat 10 x Uranium Ore 1 x Blueprint | ||||||||
| After Burner Gum | -5 |
|
-5% critical chance | Crafting 75% Level 50 Adv. Workbench |
10 x Meat Jerky 20 x High Quality Minerals 1 x Blueprint | |||||||
| Voodoo | -3 | +3 |
|
-1 LK | Crafting 75% Level 50 Adv. Workbench |
50 x Broc Flower 20 x Chemical Component 10 x Gecko Pelt 1 x Blueprint | ||||||
| Gamma Gulp Beer | +1 | -2 |
|
-1 ST | Crafting 25% Level 24 Workbench |
1 x Plastic Bottle 1 x Uranium Ore | ||||||
| Cigarettes | +1 | -1 |
|
-1 Perception | Crafting 75% Level 50 Adv. Workbench |
10 x Tobacco 10 x Fibers 1 x Blueprint ______ (using Cigarette Machine) 2 x Tobacco | ||||||
| Rot Gut | -2 | +1 |
|
-1 Endurance | Crafting 50% Level 24 Workbench |
1 x Glass Bottle 1 x Broc Flower ______ (using Still) 1 x Wood 2 x Fruit | ||||||
| Beer | -2 | +1 |
|
-1 CH | Crafting 50% Level 24 Workbench |
1 Tobacco 1 Glass bottle | ||||||
| Roentgen Rum | -2 | +1 |
|
-1 Intelligence | Crafting 50% Level 24 Workbench |
1 x Plastic Bottle 1 x Minerals | ||||||
| Nuka-Cola | -2 | +1 |
|
-1 Agility | Crafting 50% Level 24 Workbench |
1 x Glass Bottle 3 x Xander Root ______ (using Nuka-Cola Machine) 2 x Fruit 1 x Bottle with Water | ||||||
| Booze | -2 | +1 |
|
-1 Luck | Crafting 50% Level 24 Workbench |
1 x Plastic Bottle 1 x Scorpion Tail |
High-tier drugs
| PICTURE | DRUG NAME | EFFECTS |
|---|---|---|
| Cherry Nuka-Cola (T4) | Grants double damage for 10 seconds | |
| Overpsycho (T4) | Grants damage immunity for 10 seconds | |
| Trauma Pack (T4) | Revives you the next time you die | |
| Monument Chunk (T5) | Grants a 10% bonus to HP, AP, sequence, DR, DT, AC, critical chance, carry weight, healing rate, and melee damage | |
| Special Cookie (T6) | Kills the last person who killed you |
Cannibal drugs
- "Radiated" body parts can be purified with RadAway using Advanced Workbench. The purification process requires Crafting ≥ 75% and character level ≥ 50 to perform.
| Picture | Name | S | P | E | C | I | A | L | Effects | Aftereffects |
|---|---|---|---|---|---|---|---|---|---|---|
| Brain | +4 |
|
-40% max HP | |||||||
| Ear | +3 | -40% max HP | ||||||||
| Eye | +2 |
|
-40% max HP | |||||||
| Heart | +2 |
|
-40% max HP | |||||||
| Liver | +2 |
|
-40% max HP | |||||||
| Radiated Brain |
|
+200 Radiation +100 Poison | ||||||||
| Radiated Ear | +200 Radiation +100 Poison | |||||||||
| Radiated Eye | +4 | +200 Radiation +100 Poison | ||||||||
| Radiated Heart | +3 |
|
+200 Radiation +100 Poison | |||||||
| Radiated Liver | +200 Radiation +100 Poison | |||||||||
| Dead Rat |
|
n/a | ||||||||
| Blood Pack |
|
n/a | ||||||||
| Radiated Blood Pack |
|
n/a |
| Picture | Name | Effect |
|---|---|---|
| Perfect Head | GM vision (you can see everyone on the map) | |
| Royal Blood | Restores 2% HP every 0.5s until you're fully healed (3000ms attack delay) | |
| Human Guts | Sets all your SPECIAL to 20 for ten seconds |
- T4 cannibal drugs can be found in the Lost Hill dungeon.






























