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Benefit Gives you the ability to consume powerful Cannibal Drugs.
Penalty Removes your ability to consume regular drugs.

The harshness of the wasteland brought hunger and famine, so you learned to become stronger by feasting on human parts. However, you can no longer experience the effects of normal drugs.

Note: The loss of health from the timer of Cannibal Drugs running out can be negated by using Drug Antidote. (You will still lose 50 HP from using it though)