Drugs
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Drugs are wondrous objects that allow you to trade your long-term well-being for immediate survival.
Unlike regular consumables, many drugs have a chance of making you Addicted.
Chem Reliant characters automatically become addicted to whatever drugs they use, always suffering stat penalties between doses.
Drug effects wear off after a while, as indicated by an on-screen countdown timer which can be reset at any time by taking another dose.
Healing drugs
| Picture | Name | Effects | Attack delay |
Addiction | Crafting requirements |
Required materials |
|---|---|---|---|---|---|---|
| Weak Healing Powder | +30 HP | 800 | N/A | Crafting 25% Level 5 |
1 x Broc Flower 1 x Xander Root | |
| Stimpak | +50 HP | 1000 | N/A | Crafting 50% Level 24 Workbench |
2 x Broc Flower 2 x Xander Root 1 x Chemical component | |
| Super Stimpak | +80 HP | 1300 | N/A | Crafting 75% Level 50 Adv. Workbench |
1 x Meat Jerky 1 x Chemical component 1 x Blueprint | |
| Mega Stimpak | +110 HP | 1300 | N/A | Crafting 150% Level 250 Adv. Workbench |
40 x High Quality Chemical Component 20 x Electronic Parts 30 x Refined Uranium Ore 100 x Xander Root 1 x Blueprint |
Utility drugs
| Picture | Name | Effects | Addiction | Crafting requirements |
Required materials |
|---|---|---|---|---|---|
| Antidote | -25 to Poison Level removes Slow instantly |
N/A | Crafting 25% Level 5 |
1 x Scorpion Tail 1 x Plastic Bottle | |
| Drug Antidote | Removes drugs effects and addictions. | N/A | Crafting 150% Level 250 Adv. Workbench |
50 x High Quality Chemical Component 40 x Meat Jerky 10 x Glass Bottle 1 x Blueprint | |
| Rad-X | +50% Rad Resistance +10% Rad Resistance Cap -5% max hit chance -5% critical chance |
N/A | Crafting 75% Level 50 Adv. Workbench |
2 x Chemical Component 1 x Blueprint | |
| RadAway | -50 Radiation | 10% chance | Crafting 50% Level 24 Workbench |
2 x Chemical Component 3 x Minerals 1 x Blueprint |
Regular drugs
| Picture | Name | S | P | E | C | I | A | L | Effects | Addiction | Crafting requirements |
Required materials |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jet | +2 AP +4 AP for moving in turnbased * Grants +10% movement speed when using melee. -10% Normal DR |
-1 AP | Crafting 75% Level 50 Adv. Workbench |
20 x Brahmin Shit 10 x Chemical Component 1 x Blueprint | ||||||||
| Mentats | +2 | +2 | +10 Sequence +2 IN +2 CH +15% Critical Chance Resistance Penetration. +20 Healing Rate Time |
-1 CH | Crafting 75% Level 50 Adv. Workbench |
30 x High Quality Chemical Component 1 x Blueprint | ||||||
| Buffout | +2 | +2 | +2 ST +2 EN -1 AP -25 AP Regen |
-1 EN | Crafting 75% Level 50 Adv. Workbench |
10 x Meat 10 x Meat Jerky 1 x Blueprint | ||||||
| Healing Powder | -3 | +25 Healing Rate -5 Healing Rate Time -5% Damage Deal -3 LK |
-10 Healing Rate | Crafting 75% Level 50 Adv. Workbench |
5 x Broc Flower 5 x Xander Root 1 x Blueprint | |||||||
| Psycho | -3 | 5% All DR +5% Damage Reduction -50 HP -3 PE |
-3% All DR | Crafting 75% Level 50 Adv. Workbench |
10 x Meat 30 x Chemical Component 1 x Blueprint | |||||||
| Mutie | +4 All DT -10% Slow power Halves the duration of Slow +10 Heavy Handed Resistance -1 AP |
-3 All DT | Crafting 75% Level 50 Adv. Workbench |
10 x Meat 10 x Uranium Ore 1 x Blueprint | ||||||||
| After Burner gum | -5 | +10% Critical Chance -5 LK * Ignore critical chance resistances on burst * Double critical damage from table on burst |
-5% Critical Chance | Crafting 75% Level 50 Adv. Workbench |
10 x Meat Jerky 20 x High Quality Minerals 1 x Blueprint | |||||||
| Voodoo | -3 | +3 | +3 LK +10 Critical Roll(Flat) +20% AP per kill (bloodymess effect) * Unlocks the last two critical tiers. -3 EN |
-1 LK | Crafting 75% Level 50 Adv. Workbench |
50 x Broc Flower 20 x Chemical Component 10 x Gecko Pelt 1 x Blueprint | ||||||
| Gamma Gulp Beer | +1 | -2 | +5% Plasma DR +1 ST -2 PE |
-1 ST | Crafting 25% Level 24 Workbench |
1 x Plastic Bottle 1 x Uranium Ore | ||||||
| Cigarettes | +1 | -1 | +1 PE +5 Critical Chance Resistance -30 Armor Class +3 weapon range for ranged weapons. -1 CH |
-1 PE | Crafting 75% Level 50 Adv. Workbench |
10 x Tobacco 10 x Fibers 1 x Blueprint ______ (using Cigarette Machine) 2 x Tobacco | ||||||
| Rot Gut | -2 | +1 | +5% Explosive DR +1 EN -2 PE |
-1 EN | Crafting 50% Level 24 Workbench |
1 x Glass Bottle 1 x Broc Flower ______ (using Still) 1 x Wood 2 x Fruit | ||||||
| Beer | -2 | +1 | +5% Normal DR +1 CH -2 PE |
-1 CH | Crafting 50% Level 24 Workbench |
1 Tobacco 1 Glass bottle | ||||||
| Roentgen Rum | -2 | +1 | +5% Fire DR +1 IN -2 PE |
-1 IN | Crafting 50% Level 24 Workbench |
1 x Plastic Bottle 1 x Minerals | ||||||
| Nuka-Cola | -2 | +1 | +5% Electro DR +1 AG -2 PE |
-1 AG | Crafting 50% Level 24 Workbench |
1 x Glass Bottle 3 x Xander Root ______ (using Nuka-Cola Machine) 2 x Fruit 1 x Bottle with Water | ||||||
| Booze | -2 | +1 | +5% Laser DR +1 LK -2 PE |
-1 LK | Crafting 50% Level 24 Workbench |
1 x Plastic Bottle 1 x Scorpion Tail |
Tier 4 drugs
| PICTURE | DRUG NAME | EFFECTS |
|---|---|---|
| Cherry Nuka-Cola | Deal double damage for 10 seconds | |
| Hypo | Heal 50% hit points; 1000ms attack delay | |
| Monument Chunk | Grants a 10% bonus to HP, AP, sequence, DR, DT, AC, critical chance, carry weight, Healing Rate, and melee damage | |
| Overpsycho | Grants immune for 10 seconds | |
| Special Cookie | Kills the last person who killed you | |
| Trauma Pack | Revive after death |
Cannibal drugs
- "Radiated" body parts can be purified with RadAway using Advanced Workbench. The purification process requires Crafting ≥ 75% and character level ≥ 50 to perform.
| Picture | Name | S | P | E | C | I | A | L | Effects | Aftereffects |
|---|---|---|---|---|---|---|---|---|---|---|
| Dead Rat | +20 HP | +20 HP | ||||||||
| Brain | +4 | +4 IN +5% Movement Speed - Enemies deal +4 damage per bullet more |
-125 HP on out | |||||||
| Ear | +3 | +3 LK +2 AP * Unlocks the last two critical tiers. +40% Critical Damage -33% Critical Chance Resistance |
-125 HP on out | |||||||
| Eye | +2 | +2 PE -10% Attack Speed -1 AP cost -50% received heal |
-125 HP on out | |||||||
| Heart | +2 | +2 EN +15 Critical Effect Chance +100 HP cap in Critical Hit Penatly -5% to all DR |
-125 HP on out | |||||||
| Liver | +2 | +2 ST +10 Lethal Damage +5% Lethal Penetration -2 to all DT |
-125 HP on out | |||||||
| Radiated Brain | +50 Armor Class -5% max chance to hit for opponents +20 AP Regen -30 Healing Rate |
+200 Radiation Level | ||||||||
| Radiated Ear | +50 Sneak +20% Damage Multi when Sneaking +2 Damage per Bullet when Sneaking -50 HP |
+200 Radiation Level | ||||||||
| Radiated Eye | +4 | +4 CH +5 Sight +5% Slow Power -20% Critical Power Resistance |
+200 Radiation Level | |||||||
| Radiated Heart | +3 | +3 AG +8% Critical Chance +5 Critical roll +15% Damage Multi for opponents |
+200 Radiation Level | |||||||
| Radiated Liver | +50% Rad Resistance +5% DR penetration(Normal, Fire, Explode) +10% DT penetration(Normal, Fire, Explode) +10 Lethal Damage for opponents |
+200 Radiation Level | ||||||||
| Blood Pack | Normal drawback: -40% Max HP (1600ms attack delay) | |||||||||
| Radiated Blood Pack | Rad drawback: +200 Radiation Level +100 Poisoned Level |
N/A |
| Picture | Name | Effects | Aftereffects |
|---|---|---|---|
| Perfect Head | GM vision (no fog of war) | ??? | |
| Royal Blood | Restores 2% HP every 0.5s until you're fully healed (3000ms attack delay) | ??? | |
| Human Guts | Sets all your S.P.E.C.I.A.L. to 20 for ten seconds | ??? |
- T4 cannibal drugs can be found in the Lost Hill dungeon.






























