Drugs

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Drugs are wondrous objects that allow you to trade your long-term well-being for immediate survival.

Drug effects wear off after a while, as indicated by an on-screen countdown timer which can be reset at any time by taking another dose.

Cannibal drugs can only be consumed by characters with the Cannibal trait.

Characters with the Chem Reliant trait automatically become addicted to whatever drugs they use, always suffering stat penalties between doses. Regular characters cannot become addicted to drugs.

Regulators with the Chem Reliant trait experience drugs differently from regular characters; see Regulator for details.

Healing drugs

Image Name Effects Attack
delay
Crafting
requirements
Required materials
Healpwdr.gif
Weak Healing Powder +30 HP 800 ms
Stimx.gif
Stimpak +50 HP 1000 ms
Stimpak.gif
Super Stimpak +80 HP 1300 ms
Ultrastimpack.png
Mega Stimpak (T4) +110 HP 1300 ms
Hypo.png
Hypo (T5) +50% HP 1000 ms

Utility drugs

Image Name Effects Addiction Crafting
requirements
Required materials
Drug bot.gif
Antidote
—
Jetanti.gif
Drug Antidote
—
Med-Tec Antidote.png Med-Tec Antidote
  • Removes all negative status effects (Weakness, Confusion, etc.)
—
—
—
Drg rad2.gif
Rad-X
—
RadAway.gif
RadAway
  • Reduces your irradiation level by 50% of its current value
    (Cooldown: 15 minutes, can be cleared like any other drug timer)
-25% radiation resistance

Regular drugs

Image Name Effects Addiction Crafting
requirements
Required materials
SPECIAL Other
AfterBurnerGum.gif
After Burner Gum
  • +10% critical chance
  • Your bursts ignore targets' critical chance resistances
  • Your bursts deal double the normal critical damage
-5% critical chance
Beer.gif
Beer
  • +5% normal DR
-1 CH
Schlager.gif
Booze
  • +5% laser DR
-1 Luck
Dxboost2.gif
Buffout -1 EN
Cigarettes.gif
Cigarettes
  • +5 critical chance resistance
  • -30 armor class
  • +3 weapon range (ranged weapons only)
-1 Perception
Gamabeer.gif
Gamma Gulp Beer
  • +5% plasma DR
-1 ST
Healpwdr.gif
Healing Powder -10 healing rate
Jet.gif
Jet
—
-1 AP
Syring2.gif
Mentats -1 Charisma
Mutie.gif
Mutie
—
-3 to all DTs
Bottle.gif
Nuka-Cola
  • +5% electro DR
-1 Agility
Lastdrug.gif
Psycho -3% to all DRs
Roenbeer.gif
Roentgen Rum
  • +5% fire DR
-1 Intelligence
Gutrot.gif
Rot Gut
  • +5% explosive DR
-1 Endurance
Voodoo.gif
Voodoo -1 LK

High-tier drugs

Image Name Effects
Cherry Nuka-Cola.png
Cherry Nuka-Cola (T4) Grants double damage for 10 seconds
Superpsycho.png
Overpsycho (T4) Grants damage immunity for 10 seconds
Traumapack.png
Trauma Pack (T4) Revives you the next time you die
Monument Chunk.png
Monument Chunk (T5) Grants a 10% bonus to HP, AP, sequence,
DR, DT, AC, critical chance, carry weight,
healing rate, and melee damage

Cannibal drugs

  • "Radiated" body parts can be purified with RadAway using Advanced Workbench. The purification process requires Crafting ≥ 75% and character level ≥ 50 to perform.
Cannibal healing/utility drugs
Image Name Effects
Dead Rat.png
Dead Rat
  • Restores 20 HP twice (attack delay: 800 ms)
Bpack.png
Blood Pack
  • Restores 60 HP twice (attack delay: 1600 ms)
BpackRad.png
Radiated Blood Pack
  • -100 Radiation*
Cannibal drugs
Image Name Effects Aftereffects
SPECIAL Other
Brain.png
Brain +4 Intelligence -40% max HP
Ear.png
Ear +3 Luck
  • +2 AP
  • Unlocks the last two critical tiers
  • +40% critical damage
  • -33% critical chance resistance
-40% max HP
Eye.png
Eye +2 Perception -40% max HP
Heart.png
Heart +2 Endurance -40% max HP
Liver.png
Liver +2 Strength -40% max HP
BrainRad.png
Radiated Brain
—
+200 Radiation*
+100 Poison
EarRad.png
Radiated Ear
—
  • +8 Stealth
  • +20% damage multiplier when sneaking
  • +2 damage per bullet when sneaking
  • -35 HP
+200 Radiation*
+100 Poison
EyeRad.png
Radiated Eye +4 Charisma
  • +5 Sight
  • +5% Slow power
  • -20% critical power resistance
+200 Radiation*
+100 Poison
HeartRad.png
Radiated Heart +3 Agility +200 Radiation*
+100 Poison
LiverRad.png
Radiated Liver
—
  • +50% radiation resistance
  • +5% DR penetration (normal, fire, explosive)
  • +10% DT penetration (normal, fire, explosive)
  • Attackers deal +10 lethal damage to you
+200 Radiation*
+100 Poison

*- The game tracks irradiation internally in points, which the HUD then converts into a percentage (18 points = 1%). Thus, +200 "Radiation" ≈ +11% displayed irradiation.

High-tier Cannibal drugs
Image Name Effects
Humanhead.png
Perfect Head Grants GM vision for 10 seconds, allowing you to see every other player character on the map
Royalblood.png
Royal Blood Restores 2% of your maximum HP every 0.5 seconds until you are fully healed (3000 ms attack delay)
Human Guts.png
Human Guts Sets all of your SPECIAL to 20 for 10 seconds