Drugs

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Revision as of 23:18, 25 December 2025 by Faster (talk | contribs) (Updated recipes (Patch 6.4))
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Drugs are wondrous objects that allow you to trade your long-term well-being for immediate survival.

Unlike regular consumables, many drugs have a chance of making you Addicted.

Chem Reliant characters automatically become addicted to whatever drugs they use, always suffering stat penalties between doses.

Drug effects wear off after a while, as indicated by an on-screen countdown timer which can be reset at any time by taking another dose.

Healing drugs

Picture Name Effects Addiction Crafting
requirements
Required materials Required tools
Healpwdr.gif
Weak Healing Powder +30 HP N/A Crafting 25%
Level 5
1 x Broc Flower
1 x Xander Root
Anywhere
Stimx.gif
Stimpak +50 HP N/A Crafting 50%
Level 24
2 x Broc Flower
2 x Xander Root
1 x Chemical component
Workbench
Stimpak.gif
Super Stimpak +80 HP N/A Crafting 75%
Level 50
1 x Meat Jerky
1 x Chemical component
1 x Blueprint
Advanced Workbench
Ultrastimpack.png
Mega Stimpak +110 HP N/A Crafting 150%
Level 250
40 x High Quality Chemical Component
20 x Electronic Parts
30 x Refined Uranium Ore
100 x Xander Root
1 x Blueprint
Advanced Workbench

Utility drugs

Picture Name Effects Addiction Crafting
requirements
Required materials Required tools
Drug bot.gif
Antidote -25 to Poison Level
removes Slow instantly
N/A Crafting 25%
Level 5
1 x Scorpion Tail
1 x Plastic Bottle
Anywhere
Jetanti.gif
Drug Antidote Removes drugs effects and addictions. N/A Crafting 150%
Level 250
50 x High Quality Chemical Component
40 x Meat Jerky
10 x Glass Bottle
1 x Blueprint
Advanced Workbench
Drg rad2.gif
Rad-X +50% Rad Resistance
+10% Rad Resistance Cap
-5% max hit chance
-5% critical chance
N/A Crafting 75%
Level 50
2 x Chemical Component
1 x Blueprint
Advanced Workbench
RadAway.gif
RadAway -50 Radiation 10% chance Crafting 50%
Level 24
2 x Chemical Component
3 x Minerals
1 x Blueprint
Workbench

Regular drugs

Picture Name S P E C I A L Effects Addiction Crafting
requirements
Required materials Required tools
Jet.gif
Jet +2 AP
+4 AP for moving in turnbased
* Grants +10% movement speed when using melee.
-10% Normal DR
-1 AP Crafting 75%
Level 50
20 x Brahmin Shit
10 x Chemical Component
1 x Blueprint
Advanced Workbench
Syring2.gif
Mentats +2 +2 +10 Sequence
+2 IN
+2 CH
+15% Critical Chance Resistance Penetration.
+20 Healing Rate Time
-1 CH Crafting 75%
Level 50
30 x High Quality Chemical Component
1 x Blueprint
Advanced Workbench
Dxboost2.gif
Buffout +2 +2 +2 ST
+2 EN
-1 AP
-25 AP Regen
-1 EN Crafting 75%
Level 50
10 x Meat
10 x Meat Jerky
1 x Blueprint
Advanced Workbench
Healpwdr.gif
Healing Powder -3 +25 Healing Rate
-5 Healing Rate Time
-5% Damage Deal
-3 LK
-10 Healing Rate Crafting 75%
Level 50
5 x Broc Flower
5 x Xander Root
1 x Blueprint
Anywhere
Lastdrug.gif
Psycho -3 5% All DR
+5% Damage Reduction
-50 HP
-3 PE
-3% All DR Crafting 75%
Level 50
10 x Meat
30 x Chemical Component
1 x Blueprint
Advanced Workbench
Mutie.gif
Mutie +4 All DT
-10% Slow power
Halves the duration of Slow
+10 Heavy Handed Resistance
-1 AP
-3 All DT Crafting 75%
Level 50
10 x Meat
10 x Uranium Ore
1 x Blueprint
Advanced Workbench
AfterBurnerGum.gif
After Burner gum -5 +10% Critical Chance
-5 LK
* Ignore critical chance resistances on burst
* Double critical damage from table on burst
-5% Critical Chance Crafting 75%
Level 50
10 x Meat Jerky
20 x High Quality Minerals
1 x Blueprint
Advanced Workbench
Voodoo.gif
Voodoo -3 +3 +3 LK
+10 Critical Roll(Flat)
+20% AP per kill (bloodymess effect)
* Unlocks the last two critical tiers.
-3 EN
-1 LK Crafting 75%
Level 50
50 x Broc Flower
20 x Chemical Component
10 x Gecko Pelt
1 x Blueprint
Advanced Workbench
Gamabeer.gif
Gamma Gulp Beer +1 -2 +5% Plasma DR
+1 ST
-2 PE
-1 ST Crafting 25%
Level 24
1 x Plastic Bottle
1 x Uranium Ore
Workbench
Cigarettes.gif
Cigarettes +1 -1 +1 PE
+5 Critical Chance Resistance
-30 Armor Class
+3 weapon range for ranged weapons.
-1 CH
-1 PE None 2 x Tobacco
______
10 x Tobacco
10 x Fibers
1 x Blueprint
Cigarette Machine
______
Advanced Workbench
Gutrot.gif
Rot Gut -2 +1 +5% Explosive DR
+1 EN
-2 PE
-1 EN Crafting 50%
Level 24
1 x Wood
2 x Fruit
______
1 x Glass Bottle
1 x Broc Flower
Still
______
Workbench
Beer.gif
Beer -2 +1 +5% Normal DR
+1 CH
-2 PE
-1 CH Crafting 50%
Level 24
1 Tobacco
1 Glass bottle
Workbench
Roenbeer.gif
Roentgen Rum -2 +1 +5% Fire DR
+1 IN
-2 PE
-1 IN Crafting 50%
Level 24
1 x Plastic Bottle
1 x Minerals
Workbench
Bottle.gif
Nuka-Cola -2 +1 +5% Electro DR
+1 AG
-2 PE
-1 AG Crafting 50%
Level 24
2 x Fruit
1 x Bottle with Water
______
1 x Glass Bottle
3 x Xander Root
Nuka-Cola Machine
______
Workbench
Schlager.gif
Booze -2 +1 +5% Laser DR
+1 LK
-2 PE
-1 LK Crafting 50%
Level 24
1 x Plastic Bottle
1 x Scorpion Tail
Workbench

Tier 4 drugs

PICTURE DRUG NAME EFFECTS
Cherry Nuka-Cola.png
Cherry Nuka-Cola Deal double damage for 10 seconds
Hypo.png
Hypo Heal 50% hit points
Superpsycho.png
Overpsycho Grants immune for 10 seconds
Special Cookie Kills the last person who killed you
Traumapack.png
Trauma Pack Revive after death

Cannibal drugs

  • "Radiated" body parts can be purified with RadAway using Advanced Workbench. The purification process requires Crafting ≥ 75% and character level ≥ 50 to perform.
Cannibal drugs
Picture Name S P E C I A L Effects Aftereffects
Dead Rat.png
Dead Rat +20 HP +20 HP
Brain.png
Brain +4 +4 IN
+5% Movement Speed
- Enemies deal +4 damage per bullet more
-125 HP on out
Ear.png
Ear +3 +3 LK
+2 AP
* Unlocks the last two critical tiers.
+40% Critical Damage
-33% Critical Chance Resistance
-125 HP on out
Eye.png
Eye +2 +2 PE
-10% Attack Speed
-1 AP cost
-50% received heal
-125 HP on out
Heart.png
Heart +2 +2 EN
+15 Critical Effect Chance
+100 HP cap in Critical Hit Penatly
-5% to all DR
-125 HP on out
Liver.png
Liver +2 +2 ST
+10 Lethal Damage
+5% Lethal Penetration
-2 to all DT
-125 HP on out
BrainRad.png
Radiated Brain +50 Armor Class
-5% max chance to hit for opponents
+20 AP Regen
-30 Healing Rate
+200 Radiation Level
EarRad.png
Radiated Ear +50 Sneak
+20% Damage Multi when Sneaking
+2 Damage per Bullet when Sneaking
-50 HP
+200 Radiation Level
EyeRad.png
Radiated Eye +4 +4 CH
+5 Sight
+5% Slow Power
-20% Critical Power Resistance
+200 Radiation Level
HeartRad.png
Radiated Heart +3 +3 AG
+8% Critical Chance
+5 Critical roll
+15% Damage Multi for opponents
+200 Radiation Level
LiverRad.png
Radiated Liver +50% Rad Resistance
+5% DR penetration(Normal, Fire, Explode)
+10% DT penetration(Normal, Fire, Explode)
+10 Lethal Damage for opponents
+200 Radiation Level
Bpack.png
Blood Pack Normal drawback: -40% Max HP N/A
BpackRad.png
Radiated Blood Pack Rad drawback: +200 Radiation Level
+100 Poisoned Level
N/A
Tier 4 Cannibal drugs
Picture Name Effects Aftereffects
Humanhead.png
Perfect Head GM vision (no fog of war) ???
Royalblood.png
Royal Blood Restores 2% HP every 0.5s until you're fully healed ???
Human Guts Sets all your S.P.E.C.I.A.L. to 20 for ten seconds ???
  • T4 cannibal drugs can be found in the Lost Hill dungeon.