Drugs
Drugs are wondrous objects that allow you to trade your long-term well-being for immediate survival.
Drug effects wear off after a while, as indicated by an on-screen countdown timer which can be reset at any time by taking another dose.
Cannibal drugs can only be consumed by characters with the Cannibal trait.
Characters with the Chem Reliant trait automatically become addicted to whatever drugs they use, always suffering stat penalties between doses. Regular characters cannot become addicted to drugs.
Regulators with the Chem Reliant trait experience drugs differently from regular characters; see Regulator for details.
Healing drugs
| Image | Name | Effects | Attack delay |
Crafting requirements |
Required materials |
|---|---|---|---|---|---|
| Weak Healing Powder | +30 HP | 800 ms |
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| Stimpak | +50 HP | 1000 ms |
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| Super Stimpak | +80 HP | 1300 ms |
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| Mega Stimpak (T4) | +110 HP | 1300 ms |
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| Hypo (T5) | +50% HP | 1000 ms |
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Utility drugs
| Image | Name | Effects | Addiction | Crafting requirements |
Required materials |
|---|---|---|---|---|---|
| Antidote |
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| Drug Antidote |
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| Med-Tec Antidote |
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| Rad-X |
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| RadAway |
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-25% radiation resistance |
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Regular drugs
| Image | Name | Effects | Addiction | Crafting requirements |
Required materials | |
|---|---|---|---|---|---|---|
| SPECIAL | Other | |||||
| After Burner Gum |
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-5% critical chance |
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| Beer |
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-1 CH |
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| Booze |
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-1 Luck |
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| Buffout | -1 EN |
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| Cigarettes |
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-1 Perception |
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| Gamma Gulp Beer |
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-1 ST |
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| Healing Powder |
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-10 healing rate |
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| Jet |
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-1 AP |
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| Mentats |
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-1 Charisma |
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| Mutie |
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-3 to all DTs |
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| Nuka-Cola |
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-1 Agility |
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| Psycho |
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-3% to all DRs |
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| Roentgen Rum |
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-1 Intelligence |
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| Rot Gut |
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-1 Endurance |
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| Voodoo |
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-1 LK |
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High-tier drugs
| Image | Name | Effects |
|---|---|---|
| Cherry Nuka-Cola (T4) | Grants double damage for 10 seconds | |
| Overpsycho (T4) | Grants damage immunity for 10 seconds | |
| Trauma Pack (T4) | Revives you the next time you die | |
| Monument Chunk (T5) | Grants a 10% bonus to HP, AP, sequence, DR, DT, AC, critical chance, carry weight, healing rate, and melee damage | |
| Special Cookie (T6) | Kills the last person who killed you |
Cannibal drugs
- "Radiated" body parts can be purified with RadAway using Advanced Workbench. The purification process requires Crafting ≥ 75% and character level ≥ 50 to perform.
| Image | Name | Effects |
|---|---|---|
| Dead Rat |
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| Blood Pack |
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| Radiated Blood Pack |
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| Image | Name | Effects | Aftereffects | |
|---|---|---|---|---|
| SPECIAL | Other | |||
| Brain | +4 Intelligence |
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-40% max HP | |
| Ear | +3 Luck |
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-40% max HP | |
| Eye | +2 Perception |
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-40% max HP | |
| Heart | +2 Endurance |
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-40% max HP | |
| Liver | +2 Strength |
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-40% max HP | |
| Radiated Brain |
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+200 Radiation* +100 Poison | ||
| Radiated Ear | +200 Radiation* +100 Poison | |||
| Radiated Eye | +4 Charisma | +200 Radiation* +100 Poison | ||
| Radiated Heart | +3 Agility |
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+200 Radiation* +100 Poison | |
| Radiated Liver | +200 Radiation* +100 Poison | |||
*- The game tracks irradiation internally in points, which the HUD then converts into a percentage (18 points = 1%). Thus, +200 "Radiation" ≈ +11% displayed irradiation.
| Image | Name | Effects |
|---|---|---|
| Perfect Head | Grants GM vision for 10 seconds, allowing you to see every other player character on the map | |
| Royal Blood | Restores 2% of your maximum HP every 0.5 seconds until you are fully healed (3000 ms attack delay) | |
| Human Guts | Sets all of your SPECIAL to 20 for 10 seconds |






























