Drugs

Drugs are wondrous objects that allow you to trade your long-term well-being for immediate survival.

Chem Reliant characters automatically become addicted to whatever drugs they use, always suffering stat penalties between doses. Regular characters cannot become addicted to drugs.

Drug effects wear off after a while, as indicated by an on-screen countdown timer which can be reset at any time by taking another dose.

Healing drugs

Image	Name	Effects	Attack delay	Crafting requirements	Required materials
	Weak Healing Powder	+30 HP	800 ms	Crafting 25% Level 5	1 x Broc Flower 1 x Xander Root
	Stimpak	+50 HP	1000 ms	Crafting 50% Level 24 Workbench	2 x Broc Flower 2 x Xander Root 1 x Chemical component
	Super Stimpak	+80 HP	1300 ms	Crafting 75% Level 50 Adv. Workbench	1 x Meat Jerky 1 x Chemical component 1 x Blueprints
	Mega Stimpak	+110 HP	1300 ms	Crafting 150% Level 250 Adv. Workbench	40 x High Quality Chemical Component 20 x Electronic Parts 30 x Refined Uranium Ore 100 x Xander Root 1 x Blueprints
	Hypo (T5)	+50% HP	1000 ms	Crafting 300% Level 750 High Tech Workbench	10 x Goretex 100 x High Quality Chemical Component 1 x Blueprints

Utility drugs

Image	Name	Effects	Addiction	Crafting requirements	Required materials
	Antidote	Removes 25 Poison stacks Removes Slow	—	Crafting 25% Level 5	1 x Scorpion Tail 1 x Plastic Bottle
	Drug Antidote	Removes all drug effects and addictions	—	Crafting 150% Level 250 Adv. Workbench	50 x High Quality Chemical Component 40 x Meat Jerky 10 x Glass Bottle 1 x Blueprints
	Med-Tec Antidote	Removes all negative status effects (Weakness, Confusion, etc.)	—	—	—
	Rad-X	+50% radiation resistance +10% radiation resistance cap -5% maximum hit chance -5% critical chance	—	Crafting 75% Level 50 Adv. Workbench	2 x Chemical Component 1 x Blueprints
	RadAway	Reduces your irradiation level by 50% of its current value (Cooldown: 15 minutes, can be cleared like any other drug timer)	-25% radiation resistance	Crafting 50% Level 24 Workbench	2 x Chemical Component 3 x Minerals 1 x Blueprints

Regular drugs

Image	Name	S	P	E	C	I	A	L	Effects	Addiction	Crafting requirements	Required materials
	Jet								+2 APs +4 TB movement APs +10% movement speed (melee only) -10% normal DR	-1 AP	Crafting 75% Level 50 Adv. Workbench	20 x Brahmin Shit 10 x Chemical Component 1 x Blueprints
	Mentats				+2	+2			+10 Sequence +2 Intelligence +2 Charisma +15% critical chance resistance penetration +20 seconds to healing rate cooldown	-1 Charisma	Crafting 75% Level 50 Adv. Workbench	30 x High Quality Chemical Component 1 x Blueprints
	Buffout	+2		+2					+2 Strength +2 Endurance -1 AP -25 AP Regen	-1 EN	Crafting 75% Level 50 Adv. Workbench	10 x Meat 10 x Meat Jerky 1 x Blueprints
	Healing Powder							-3	+25 healing rate -5 healing rate cooldown -5% damage -3 Luck	-10 healing rate	Crafting 75% Level 50 Adv. Workbench	5 x Broc Flower 5 x Xander Root 1 x Blueprints
	Psycho		-3						+5% to all DRs +5% damage protection -35 HP -3 Perception	-3% to all DRs	Crafting 75% Level 50 Adv. Workbench	10 x Meat 30 x Chemical Component 1 x Blueprints
	Mutie								+4 to all DTs -10% to attackers' Slow power Halves the duration of Slow on you +10 Heavy Handed resistance -1 AP	-3 to all DTs	Crafting 75% Level 50 Adv. Workbench	10 x Meat 10 x Uranium Ore 1 x Blueprints
	After Burner Gum							-5	+10% critical chance -5 Luck Your bursts ignore targets' critical chance resistances Your bursts deal double the normal critical damage	-5% critical chance	Crafting 75% Level 50 Adv. Workbench	10 x Meat Jerky 20 x High Quality Minerals 1 x Blueprints
	Voodoo			-3				+3	+3 Luck +10 critical roll Recover 20% APs on kill (Bloody Mess effect) Unlocks the last two critical tiers -3 Endurance	-1 LK	Crafting 75% Level 50 Adv. Workbench	50 x Broc Flower 20 x Chemical Component 10 x Gecko Pelt 1 x Blueprints
	Gamma Gulp Beer	+1	-2						+5% plasma DR +1 Strength -2 Perception	-1 ST	Crafting 25% Level 24 Workbench	1 x Plastic Bottle 1 x Uranium Ore
	Cigarettes		+1		-1				+1 Perception +5 critical chance resistance -30 armor class +3 weapon range (ranged weapons only) -1 Charisma	-1 Perception	Crafting 75% Level 50 Adv. Workbench	Workbench recipe: 10 x Tobacco 10 x Fibers 1 x Blueprints Cigarette Machine recipe: 2 x Tobacco
	Rot Gut		-2	+1					+5% explosive DR +1 Endurance -2 Perception	-1 Endurance	Crafting 50% Level 24 Workbench	Workbench recipe: 1 x Glass Bottle 1 x Broc Flower Still recipe: 1 x Wood 2 x Fruit
	Beer		-2		+1				+5% normal DR +1 Charisma -2 Perception	-1 CH	Crafting 50% Level 24 Workbench	1 Tobacco 1 Glass bottle
	Roentgen Rum		-2			+1			+5% fire DR +1 Intelligence -2 Perception	-1 Intelligence	Crafting 50% Level 24 Workbench	1 x Plastic Bottle 1 x Minerals
	Nuka-Cola		-2				+1		+5% electro DR +1 Agility -2 Perception	-1 Agility	Crafting 50% Level 24 Workbench	Workbench recipe: 1 x Glass Bottle 3 x Xander Root Nuka-Cola Machine recipe: 2 x Fruit 1 x Bottle with Water
	Booze		-2					+1	+5% laser DR +1 Luck -2 Perception	-1 Luck	Crafting 50% Level 24 Workbench	1 x Plastic Bottle 1 x Scorpion Tail

High-tier drugs

Image	Name	Effects
	Cherry Nuka-Cola (T4)	Grants double damage for 10 seconds.
	Overpsycho (T4)	Grants damage immunity for 10 seconds.
	Trauma Pack (T4)	Revives you the next time you die.
	Monument Chunk (T5)	Grants a 10% bonus to HP, AP, sequence, DR, DT, AC, critical chance, carry weight, healing rate, and melee damage.
	Special Cookie (T6)	Kills the last person who killed you.

Cannibal drugs

• "Radiated" body parts can be purified with RadAway using Advanced Workbench. The purification process requires Crafting ≥ 75% and character level ≥ 50 to perform.

Cannibal drugs

Image	Name	S	P	E	C	I	A	L	Effects	Aftereffects
	Brain					+4			+4 Intelligence +5% movement speed Enemies deal +4 damage per bullet	-40% max HP
	Ear							+3	+3 Luck +2 APs Unlocks the last two critical tiers +40% critical damage -33% critical chance resistance	-40% max HP
	Eye		+2						+2 Perception -10% attack delay -1 AP cost -50% healing received	-40% max HP
	Heart			+2					+2 Endurance +15% chance to apply a critical effect +100 HP cap for critical roll penalty calculation -5% to all DRs	-40% max HP
	Liver	+2							+2 Strength +10 lethal damage +5% lethal penetration -2 to all DTs	-40% max HP
	Radiated Brain								+50 armor class -5% to attackers' max chance to hit you +20 AP Regen -30 healing rate	+200 Radiation* +100 Poison
	Radiated Ear								+8 Stealth +20% damage multiplier when sneaking +2 damage per bullet when sneaking -35 HP	+200 Radiation* +100 Poison
	Radiated Eye				+4				+4 Charisma +5 Sight +5% Slow power -20% critical power resistance	+200 Radiation* +100 Poison
	Radiated Heart						+3		+3 Agility +8% critical chance +5 critical roll +15% to attackers' damage multiplier against you	+200 Radiation* +100 Poison
	Radiated Liver								+50% radiation resistance +5% DR penetration (normal, fire, explosive) +10 DT penetration (normal, fire, explosive) Attackers deal +10 lethal damage to you	+200 Radiation* +100 Poison
	Dead Rat								Restores 20 HP twice (attack delay: 800 ms)	n/a
	Blood Pack								Restores 60 HP twice (attack delay: 1600 ms)	n/a
	Radiated Blood Pack								-100 Radiation*	n/a

*- The game tracks irradiation internally in points, which the HUD then converts into a percentage (18 points = 1%). Thus, +200 "Radiation" ≈ +11% displayed irradiation.

High-tier Cannibal drugs

Image	Name	Effect
	Perfect Head	Grants GM vision (you can see everyone on the map)
	Royal Blood	Restores 2% HP every 0.5 s until you're fully healed (3000 ms attack delay)
	Human Guts	Sets all of your SPECIAL to 20 for ten seconds

• High-tier Cannibal drugs can be found in the Lost Hill dungeon.